Genomic Annotation Lab Exercise
Dr. Marian Kaehler (Luther College), in collaboration with Jacob Jibb, has written an annotation lab. This lab will ask students to annotate a gene from the D. erecta genome.
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Gene Annotation
Pandemic Flu Genomics Exercise
Dr. Robert Moss (Wofford College) has developed an annotation exercise on Influenza viruses.
Basic BLAST and Annotation Exercises
Dr. Hui-Min Chung (University of West Florida) has posted a series of 4 worksheets which can be used as a basic introduction to BLAST and annotation. These are very basic and suitable for use prior to the GEP annotation homework #1 and #2.
Gene Annotation of Genomic DNA
Dr. James Bedard with students Amber Harlan and Joshua Machone presented a walkthrough on their annotation projects for a lunchtime talk series at Adams State College.
Detecting and Interpreting Genetic Homology
An introductory exercise using BLAST to annotate a region in the Drosophila melanogaster genome. Students can use this exercise to gain familiarity with performing BLAST searches and interpreting BLAST output. An answer key is provided for instructors.
FlyBase for Undergrads
Dr. Hui-Min Chung (University of West Florida) and her students have developed an instructional video aimed at introducing undergraduate students to the research tools available at FlyBase.
Bioinformatics Tools Tutorial Project – KRas
This lab is an updated, stand-alone version of the bioinformatics exercise originally developed for Bio 3055 at Washington University. This exercise introduces students to the genetic basis of disease using the KRas protein.
Investigating Gene Flow in Grasshopper Populations
Students use grasshoppers collected from glades in the Missouri Ozarks to generate and analyze sequence data to determine if the grasshopper populations are becoming fragmented due to the suppression of forest fires. Sequence data are provided here so students who do not have access to grasshoppers can still perform the sequence analysis portion of the lab.
Identifying Unknown Bacteria Using Biochemical and Molecular Methods
Students use two different protocols, one based on sequence analysis and one based on biochemistry, to determine the identity of an unknown bacterial strain.
Investigating a Eukaryotic Genome: Cloning and Sequencing a Fragment of Yeast DNA
This lab provides an opportunity for students to randomly clone a fragment of the yeast genome into E. coli and then investigate what part of the genome they have cloned through sequence analysis.