Chimp BAC Analysis: Genes and Pseudogene
A step-by-step tutorial that takes the student through a gene identification problem in a chimpanzee BAC sequence using predictions from a gene prediction program (Genscan), the UCSC Browser and BLAST.
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Using mRNA and EST Evidence in Annotation
This exercise allows students to learn how to use mRNA and Expressed Sequence Tags (ESTs) evidence to assist their annotation efforts. An answer key is available for instructors.
GenBank Accession Number Reference Sheet
This document describes the naming conventions used by NCBI. Students can use these naming conventions to quickly evaluate the type and the reliability of the sequences in the NCBI database.
List of Common Bioinformatics Programs
This document provides a list of web-based annotation tools (and their web addresses) available to students.
Introduction to ab initio and Evidence-based Gene Finding
This PowerPoint presentation examines the use of gene prediction programs (such as Genscan) in annotation, noting some of the limitations of gene prediction programs in creating putative gene models. It also introduces the UCSC and other browsers as sources of supporting evidence.
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