Developed by Dr. Susan Parrish (McDaniel College), this PowerPoint presentation describes how Clustal Omega can be used to produce multiple sequence alignments. The multiple sequence alignments of the nucleotide sequences surrounding the transcription start sites can be used to identify core promoter motifs, while the multiple sequence alignments of protein sequences can be used to identify conserved domains. The presentation also includes a discussion of two strategies (UPGMA and Neighbor Joining) that are often used to construct phylogenetic trees.
Archived Curriculum This curriculum is no longer being actively maintained by the GEP Curriculum Committee.
Generating Multiple Sequence Alignments with Clustal Omega
- Last Reviewed: December 21, 2021
- Last Updated: December 21, 2021
- Susan Parrish
- Created: July 23, 2017
- Curriculum Section: Bioinformatics
- Curriculum Type: Lecture
- NIBLSE Competencies: C2
- Topic Tags: Multiple Sequence Alignment
- Tool Tags: Clustal Omega